SCC on the nose

Age: 86 years

Gender: Female

Site: Nose

Duration: One year

Morphology: Pyogenic granuloma-like nodular mass with slightly vegetative fragile granular base covered with bloody crust and elevated border. No regional or distant lymph node enlargement. 

Multiple BCCs in XP

Age: 24 years
Gender: Female
Site: Face
Duration: 10 years
History: Multiple pigmented, nodular and ulcerative BCCs started to appear at prepubertal age in this woman with hereditary xeroderma pigmentosum.

B-cell lymphoma

Age: 82 years
Gender: Male
Site: Face
Duration: 1 year
History: Multiple, asymptomatic, indurative and infiltrative erythematous nodules and plaques involved mainly the face and also the trunk. Mediastinal and cervical lymph nodes were involved in addition to hepatosplenomegally.

B-cell lymphoma

Age: 60 years

Gender: Male

Site: Face

Duration: 10 months

History: Asymptomatic, erythematous, indurated plaques involved both preauricular areas and forehead with no lymph node enlargement or organomegally.

Superficial BCC

Age: 68 years
Gender: Male
Site: V-area of the chest
Duration: > 1 year
History: An asymptomatic, persistent, red patch with an irregular outline and superficially eroded and partially crusted surface. Excisional biopsy revealed BCC. 

Pigmented BCC

Age: 73 years
Gender: Female
Site: Cheek
Duration: 2 years
Morphology: An asymptomatic, irregularly-shaped, pigmented nodular lesion with an elevated border.

Keratoacanthoma

Age: 61 years
Gender: Male
Site: Lower lip
Duration: 3 months
Morphology: An asymptomatic, solitary, dome-shaped nodule with keratotic surface. Excisional biopsy revealed KA.

Basal cell carcinoma

Age: 80 years
Gender: Female
Site: Nose
Duration: 1 year
History: A small persistent crusted erosion with with no tendency for spontaneous healing or resolution. Excisional biopsy confirmed BCC.

Keratoacanthoma

Age: 50 years
Gender: Male
Site: Lower lip
Duration: 3 months
Morphology: An asymptomatic, solitary, well-circumscribed, dome-shaped, pinkish, crusted nodule about one cm diameter. Excisional biopsy showed KA.

Multiple neuorofibromas

Age: 38 years
Gender: Female
Site: Back
Duration: 20 years
Morphology: Myriad of asymptomatic, flesh-colored, soft nodules with buttonholing sign. These begnin skin tumors were associated with multiple cafe-au-lait patches. 

Mycosis fungoides

Age: 46 years
Gender: Female
Site: Leg
Duration: 9 months
History: An asymptomatic, solitary, indurated and infiltrative crusted plaque having an inverted-heart shape with more activity on the marginal zone than the center.

Recurrent BCC

Age: 78 years
Gender: Male
Site: Scalp
Duration: 1 year
History: 11 years ago this man had BCC on his scalp removed surgically. Now he presents with a noduloulcerative lesion with beefy red base and pigmented rolled up border at the same site of previous lesion. Biopsy confirmed BCC.

B-cell lymphoma

Age: 69 years
Gender: Male
Site: Face & Trunk
Duration: > 2 years
History: Asymptomatic, firm to hard, infiltrative, dull red plaques and nodules. Lymph nodes enlargement and hepatomegally were positive. 

Multiple trichoepitheliomas

Age: 20 years
Gender: Female
Site: Face
Duration: Since puberty
Morphology: Asymptomatic, multiple, firm, translucent papules involved the midface especially the nasolabial folds.

Recurrent BCC

Age: 68 years
Gender: Male
Site: Scalp
Duration: Recurrent (Decades)
History: At 1950s the patient was treated with radiation therapy for favus (the treatment available for tinea capitis at that time). Many decades later (1990s) he developed BCC on his atrophic scalp. This time it was treated with surgical excision. Three years later it recurred and treated with an unwise decision with radiation therapy (10 sessions ). Now he presented with a large pigmented plaque having slightly raised border.

Bowen's disease

Age: 75 years

Gender: Female (Russian woman)

Site: Back

Duration: > 5 years.

Morphology: An asymptomatic, slowly-enlarging, well-circumscribed, slightly-infiltrative, large psoriasiform plaque. Skin biopsy showed typical histologic changes of Bowen's disease.

Advanced BCC in XP

Age: 66 years
Gender: Female
Site: Nose
Duration: 5 years
Morphology: Multiple BCCs involving the face of this woman with xeroderma pigmentosum. The main one was phagedenic ulcer with characteristic rolled up border. It has destroyed most of the nose and exposed its interior.

Pigmented BCC

Age: 66 year
Gender: Female
Duration: 1 year
Site: Nose
Morphology: An asymptomatic, blackberry-colored nodule about one cm diamter.

SCC

Age: 60 years
Gender: Male
Site: Scalp
Duration: 1 year
Morphology: An asymptomatic, firm, vegetative plaque with multinodular surface. No lymph node enlargement or distant metastasis.

Basal cell carcinoma

Age: 55 year
Gender: Female
Site: Upper lip (medial to melolabial fold)
Duration: 1 year
Morphology: An asymptomatic, non-healing, rounded, one cetimeter diameter superficial ulcer. Excisional biopsy revealed BCC.

MF (Plaque stage)

Age: 62 years
Gender: Males
Site: Face & Thigh
Duration: > 2 years
Duration: Multiple, pruritic, dull-red, infiltrative plaques involved the face, limbs and less on the trunk. No lymphadenopathy or distant metastasis.

BCC in Xeroderma pigmentosum

Age: 39 years
Gender: Female
Site: Face (Forehead)
Duration: 1 year
Morphology: A known case of XP since childhood with positive family history of similar problem in many family members. A rounded superficial ulcer with thready border and surface telangiectasia was the main presenting problem.

Pigmented BCC

Age: 60 years
Gender: Male
Site: Lower eyelid
Duration: 8-10 months
Morphology: A small ulcer with rolled up pigmented margin and easily bleeding tendency.

Multiple trichoepitheliomas

Age: 22 years
Gender: Female
Site: Face
Duration: Since early childhood
Morphology: Asymptomatic, flesh-colored, translucent, firm papules. One of the  patient's brothers has had similar lesions.

Multiple neurofibromas

Age: 67 year
Gender: Female
Site: Face
Duration: Many decades
Morphology: A known case of neurofibromatosis since early childhood. She presented with myriads of skin-colored soft nodules involving most of the face and many other parts of the body. The face mimicked a "bunch of grape" due to these tumors. The nodules were soft and can be pushed down into the panniculus by light pressure with the finger ("buttonholing") and spring back when released.

Mycosis fungoides

Age: 46 years
Gender: Female
Site: Face & Forearms
Duration: 5 years
Morphology: Asymptomatic, bilateral symmetrical, infiltrative red plaques and nodules. There was no lymph node or organ enlargement.

Pigmented BCC

Age: 77 year
Gender: Female
Site: Mandibular region
Duration: 3 years
Morphology: An oval, large ulcer with pigmented rolled up border and crusted base. The lesion bleeds easily on minor touch. There was no lymph node enlargement.

SCC

Age: 27 year
Gender: Male
Site: Lower lip
Duration: 8 months
Morphology: An asymptomatic, indurated, oval ulcer with everted borders and crusted granular base. No lymph node enlargemet or distant metastasis.

MF (Plaque stage)

Age: 43 year
Gender: Female
Site: Thigh
Duration: 1 year
Morphology: A solitary, asymptomatic, indurated, brownish-red plaque with multinodular surface and irregular well-demarcated outline.

Squamous cell carcinoma

Age: 70 years
Gender: Females
Site: Lower lip
Duration: 18 months
Morphology: Oval ulcer with an everted borders and hemorrhagic crusted base. No lymph node enlargement or organomegaly.

Noduloulcerative BCC

Age: 75 years

Gender: Male

Site: Upper lip

Duration: 2 years

Morphology: Oval noduloulcerative lesion with partially scarred center and pearly rolled up border and surface telangectasis.

Keratoacanthoma

Age: 65 years
Gender: Male
Site: Cheek
Duration: 6 months
Morphology: An asymptomatic, solitary, dome-shaped nodule with a central keratin-filled crater.

Squamous cell carcinoma

Age: 85 year
Gender: Male
Site: Lower lip
Duration: > 1 year
Morphology: Asymptomatic, hard, red multinodular mass. Two submental lymph nodes were palpable but no organ metastasis.

Mycosis fungoides (Plaque-stage)

Age: 30 year
Gender: Male
Site: Trunk & Limbs
Duration: 3 years
Morphology: Pruritic reddish-brown well-demarcated indurated plaques variable in sizes and shapes. The lymph nodes, liver, spleen and other organs were not involved.

Kaposi sarcoma

Age: 67 year
Gender: Male
Site: Palm
Duration: 7 months
Morphology: An asymptomatic, large, solitary, violaceous nodular plaque. No lymph node involvement or distant metastasis.

Nodular BCC

Age: 67 year

Gender: Female

Site: Nose

Duration: > 1 year

Morphology: An asymptomatic, skin-colored to translucent, rounded nodule with surface telangectases. 

Basal cell carcinoma

Age: 50 year
Gender: Female
Site: Lower lip
Duration: 1 year
Morphology: A crusted oval ulcer having a slightly pigmented thready margin and easily bleeding tendency.

Leiomyoma

Age: 38 year
Gender: Female
Site: Upper arm
Duration: 1 year
Morphology: Multiple, skin-colored to pinkisk tender papules and nodules that were characteristically painful on cold exposure.

Kaposi sarcoma

Age: 64 years
Gender: Male
Site: Feet
Duration: 8 months
Morphology: Asymptomatic, violaceous-purplish plaques and nodules confined to both lower limbs especially the feet. No lymph node involvement or distant metastasis.

KA with flattened surface.

Age: 20 years
Gender: Male
Site: Eyebrow
Duration: 3 months
Morphology: An asymptomatic, flesh-colored nodule having a flattened surface with central keratin-filled depression.

Noduloulcerative BCC

Age: 78 year
Gender: Male
Site: Upper lip
Duration: 5 years
Morphology: An asymptomatic large rodent ulcer with irregular outline surrounded by slightly pigmented rolled up border. No distant metastasis.

Noduloulcerative BCC

Age: 70 year
Gender: Male
Site: Nose
Duration: 3 years
Morphology: Destructive ulcer that easily bleeds on minor touch with friable granular base and rolled up border. No lymph node involvement or oganomegally.

Acral lentiginous melanoma

Age: 50 year

Gender: Female

Site: Foot side

Duration: > 1 year

Morphology: An asymptomatic, irregularly-shaped, hyperpigmented patch 8 cm in greatest diameter. Most "ABCDE" criteria of malignant melanoma are applicable to this lesion. No lymph node enlargement or distant metastasis.

Pigmented BCC

Age: 67 year
Gender: Male
Site: Lower eyelid
Duration: > 1 year
Morphology: An asymptomatic, darkly-pigmented nodule with small central ulceration having semilunar shape and rolled up border. 

Pigmented BCC

Age: 58 year

Gender: Male

Site: Neck

Duration: 5 years

Morphology: An asymptomatic blackish nodule with thready border.